During 35 years, more than 25000 surgeries were done for patients with musculoskeletal tumors in the department of tumor surgery of Shafa Orthopedic, Iranshar Hospital, and office, the primary referral center in our country. The basis of our work in these centers is early correct diagnosis and treatment of musculoskeletal tumors of these patients. We are also training residents and fellowships and research in this field of orthopedics.